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Disruptive technology changed
                                 the course of vascular surgery

                                 A leader in the field, PMCC promotes big ideas and the move toward less-invasive surgeries,
                                 individualized treatments and personalized medicine

                                 By Jennifer Hough

Illustrations by Brent Phillips  Vascular surgery was rev-                  “Every                               “There is real                        as clinicians.”
                                 olutionized in the early 1990s,          day we are                               strength in                          Indeed, the PMCC has a long
                                 when new technology allowed             questioning,
                                 surgeons to enter blood vessels           ‘How can                              numbers and                           history of medical “firsts,” from
                                 and repair aortic aneurysms from         we do this                               expertise.                          the first clinical use of heparin
                                 within.                               better?’ We are                            That’s what                          as a blood thinner in 1935, to the
                                                                       encouraged to                                                                   first pacemaker used in 1950, to
                                  “The advent of minimally-            think like that,                         drew me here –                         more recently, in 2012, when the
                                 invasive surgery – endovascular        and to always                           the ability and                        PMCC became the first in the
                                 surgery – whereby we can make            be looking                                                                   world to harvest stem cells from
                                 a small incision in the groin                                                    potential to                         a patient’s bone marrow and
                                 and remotely position an arotic            for new                                be a world-                         transplant the cells into the heart
                                 stent graft, is the most successful     solutions to                                                                  during bypass surgery.
                                 example of how disruptive              the challenges                              leader in
                                 technology radically changed             we face as                             discovery and                          “It’s this kind of research that
                                 vascular practice,” says Dr.             clinicians.”                            innovation,                          sets the groundwork others can
                                 Thomas Lindsay, Division Head                                                  and to educate                         build on, that allows modern
                                 of Vascular Surgery at the Peter                 Dr. Thomas Lindsay,             tomorrow’s                           cardiac surgery to exist,” Dr.
                                 Munk Cardiac Centre (PMCC),               Division Head of Vascular Surgery,                                          Lindsay says.
                                 based at Toronto General Hospital                                                  leaders.”
                                 and part of Toronto’s University              Peter Munk Cardiac Centre                                                Today, the promise of discovery
                                 Health Network (UHN).                                                                     Dr. Thomas Forbes,          is still alive and well.
                                                                      and science with real-life medical                    Professor and Chair,
                                  When it comes to treating           problems to advance the field.                    Division of Vascular Surgery,   “We have become a little more
                                 abdominal aortic aneurysms,                                                                University of Toronto      sophisticated and have solved
                                 which makes up the bulk of Dr.        According to Dr. Lindsay,                                                       some of the bigger problems,
                                 Lindsay’s work, it means an          who for 11 years held the Chair          are encouraged and nurtured.            so now we are looking further
                                 overnight recovery versus six        of Vascular Surgery at the               “Every day we are questioning,          out in developing much better
                                 weeks.                               University of Toronto, big ideas         ‘How can we do this better?’ We
                                                                                                               are encouraged to think like that,         InsIde the
                                  The technique uses fluorscopic                                               and to always be looking for new           vascular system
                                 X-ray imaging in the operating                                                solutions to the challenges we face
                                 room to guide a catheter                                                                                                 Responsible for carrying blood
                                 containing a tube of strong fabric                                                                                       to and from all major organs in
                                 with steel stents through the                                                                                            the body, the vascular system is
                                 arteries. Once in place, the stent                                                                                       essentially the plumbing upon
                                 is expanded and seals off the                                                                                            which all systems in the body
                                 aneurysm.                                                                                                                rely.

                                  While some more complex cases                                                                                             If the plumbing fails or is
                                 still need open heart surgery, this                                                                                      compromised, major organ
                                 minimally-invasive method is                                                                                             systems are also at risk of failing.
                                 used in the majority of cases.
                                                                                                                                                            Vascular surgeons treat
                                  Now, says Dr. Lindsay, the                                                                                              disorders of the blood vessels
                                 challenge for clinicians and                                                                                             outside of the heart and head –
                                 researchers is to individualize                                                                                          mainly blockages in arteries or
                                 treatments and move toward                                                                                               aneurysms, which are enlarged
                                 the same kind of personalized                                                                                            blood vessels most common in
                                 medicine approach being used in                                                                                          the abdominal aorta.
                                 other disciplines.
                                                                                                                                                            The Division of Vascular Surgery
                                  At the PMCC, a leading cardiac                                                                                          at Toronto General Hospital is
                                 centre that prides itself on hiring                                                                                      a world-class academic unit
                                 and retaining the best talent,                                                                                           renowned for delivering care to
                                 researchers and clinicians are                                                                                           highly complex cases through
                                 every day trying to marry research                                                                                       advanced diagnostic and surgical
                                                                                                                                                          interventions.

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