Page 27 - An Innovation Spirit ...
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Graham Nie sat down                        better-than-fighting chance when           for the patient, says Dr. Tan, because
with his doctor at the                     a large aneurysm caused a tear in          X-ray dye can be toxic to the kidneys.
Peter Munk Cardiac                         his aorta. In February 2013, doctors
Centre (PMCC) to look at                   at the PMCC implanted a stent (an           With the PMCC’s advanced
a CT scan of his heart,                    expandable tube made with fabric           imaging technology, a CT scan is
rendered in 3-D on a                       and alloy materials) into the affected     used to generate a 3-D picture of the
computer screen, a year                    artery using a tube inserted through a     aorta, which is then fused with an
after he had surgery to                    small slit in the groin. Once the stent    X-ray of the same area. The result
implant a stent in a                       was in place, a balloon tip at one end     is a complete and detailed digital
diseased artery.                           of the tube inflated it to its full size,  representation of the artery, allowing
                                           enabling it to reinforce the weakened      for precise placement of the stent
 “It was amazing. He could flip this       artery and prevent further swelling.       without further injections of X-ray
image around, so I could see where                                                    dye.
the stent and its branches were put         “Advanced EVAR is one of the most
in,” recalls Mr. Nie, who was first        significant developments in aortic          “What is unique here is our ability to
diagnosed in 1997 with an abdominal        surgery, developed elsewhere, but          offer advanced EVAR in an advanced
aortic aneurysm – a balloon-like bulge     refined at UHN,” says Dr. Kong Teng        imaging environment,” says Dr.
that can cause parts of the body’s         Tan, Division Head, Interventional         Tan, referring to the image-guided
largest blood vessel, the aorta, to swell  Radiology, Toronto General Hospital.       operating rooms (OR), which feature
and, in some cases, rupture. “It was                                                  large computer screens that give OR
the first time in many years that I was     “The conventional way is open             teams access to CT, X-ray and other
clear of aneurysms.”                       surgery, with an incision practically      images during a surgical procedure.
                                           from the top of the chest to the groin,”   “We are one of the few pioneering
 Today, Mr. Nie, a 75-year-old retired     adds Dr. Tan, noting that the PMCC         places to do it.”
school principal, remains aneurysm-        leads the country in the number of
free and continues to recover. He’s        advanced EVARs performed each               The use of CT scans in cardiology is,
active, albeit slower in his everyday      year. “It’s very invasive, so not all      in itself, a pioneering strategy that the
tasks such as mowing the lawn around       patients can go through the operation      PMCC continues to advance through
his property in Peterborough, Ont.         because you have to have a certain         research. Aside from minimizing
                                           level of health to tolerate it.”           X-ray dye injections, CT scans provide
 Mr. Nie’s successful treatment and                                                   deeper insight into the anatomy of
recovery can be attributed directly         With advanced EVAR, the PMCC              the heart, all the way down to the
to leading-edge innovations at the         can give more patients a chance to         cellular level. This allows doctors to
PMCC, particularly in advanced             get a potentially life-saving stent – an   see physiological clues and diagnose
medical imaging. From the increased        avenue that used to be closed off to       disease sooner and more precisely.
use of CT scans to diagnose and            about 80 per cent of patients with         For example, the amount of blood
address heart and vascular disease         aortic aneurysms, says Dr. Tan. But        flow to muscles in the heart might
to multimodal practitioners with           what sets the PMCC apart from many         indicate that certain arteries are
combined expertise in cardiology,          other hospitals that offer advanced        likely to continue narrowing and will
vascular surgery and radiology, the        EVAR is its use of advanced imaging        eventually stop functioning.
PMCC is driving advances in medical        during the procedure.
methods and technology to improve                                                      “By looking at the physiology, we can
patient outcomes.                           In the past, doctors had to keep          pick up disease early and characterize
                                           injecting patients undergoing EVAR         the disease to help with decision
 Located at Toronto General                with X-ray dye to ensure the stent was     making,” says Dr. Paul. “This type of
Hospital – one of four hospitals that      positioned properly. This isn't good       insight also helps us determine later if
make up Ontario’s University Health                                                   the treatment is working.”
Network (UHN) – the PMCC has a
history of innovations that goes back                                                 Advanced uses and research with
75 years. It boasts many world firsts,
from the first pacemaker implant in                                                   CT scans aren’t the only imaging
1950 to the first installation and use
of the Carto 3 heart monitor recorder                                                 innovations at the PMCC. Dr. Danna
system, which uses electromagnetic
technology to create three-                                                           Spears, Clinical Director of the
dimensional images of the heart.
                                                                                      Heritable Arrhythmia Program at
 “Everything we do is based around
how to make things better for patients                                                the PMCC, uses catheter-guiding
and for the health-care system,” says
Dr. Narinder Paul, Division Chief,                                                    technologies to map patients’ cardiac
Cardiothoracic Radiology, University
Health Network. The medical imaging                                                   electrical systems by picking up
team that also serves Toronto’s Mount
Sinai and Women’s College hospitals.                                                                  signals from an
“This means exploring and embracing
new technologies, as well as                                                          Dr. Kong        ultrasound probe
innovating through new applications                                                   Teng Tan        or by sensing
of existing technology.”                                                              and Dr. Elsie   changes in
                                                                                      Nguyen are      electrical resistance.
 In Mr. Nie’s case, the marriage of two                                               members of      Electrode patches
innovations – advanced endovascular                                                   the innovative  applied on the
aneurysm repair (EVAR) and
advanced imaging – gave him a                                                         medical         body generate a

                                                                                      imaging team. magnetic field that

                                                                                      The work of     communicates
                                                                                      Dr. Danna       with an electrode
                                                                                      Spears (near    tip on the catheter
                                                                                      left) focuses   to produce 3-D
                                                                                      on patients     images of the heart’s
                                                                                      with irregular  electrical system.
                                                                                      heartbeats.
                                                                                                       “The conventional
                                                                                                      way of imaging is

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