Page 6 - Report to Our Community 2018/19
P. 6

Elevate Canada
                         as a world destination
                         for commercialization
                         and discovery.




             UHN and


             U of T launch




             CRANIA





             New centre to advance solutions
             for diseases such as Parkinson’s
             and Alzheimer’s


             The CenteR for Advancing Neurotechnological
             Innovation to Application (CRANIA) aims to find      Drs. Milos Popovic and Taufik Valiante
             safe and permanent solutions for conditions that
             have been haunting humanity, such as Alzheimer’s,
             Parkinson’s, depression, epilepsy, chronic pain,    plinary and integrated approach that will allow us to
             spinal cord injury, amongst many others.            better understand brain dysfunctions and develop
                                                                 new solutions for our patients.”
             Just how will it do that? Through unique techno-
             logical advancements invented and made in Canada,   Currently, the state-of-the-art approach in many
             and applied to the field of neuromodulation.        areas of neuroscience typically treats an area or region,
                                                                 rather than pinpointing the source of the problem.
             Neuromodulation uses sophisticated devices that
             can be implanted in a patient’s brain, spinal cord or   “It’s like giving antibiotics to a whole city because
             peripheral nerves. These devices modulate neuronal   one person has an infection,” says  Dr. Milos Popovic,
             activity, either through electric, or chemical      Research Director at the Toronto Rehabilitation
             stimulus. They can help control tremors from        Institute (TRI) and the co-founder of CRANIA.
             Parkinson’s, relieve chronic pain or even improve   “We end up hitting a lot more neurons than we
             bladder control. It is a field that is progressing   need to, healthy neurons… At CRANIA we will
             rapidly in medicine.                                drastically improve accuracy and precision of
                                                                 treatments, targeting only the diseased neurons, and
             Dr. Taufik Valiante, scientist at the Krembil
             Research Institute, neurosurgeon at Toronto         preserving many more of the already healthy ones.”
             Western Hospital and co-founder of CRANIA,
             says that although Canada has a strong tradition    CRANIA researchers are using highly-advanced
             of research in healthcare, it has lagged behind in   technologies to better understand how these
             neuromodulation development and commercial-         diseases affect the brain. By analyzing this data
             ization. CRANIA is changing that.                   using machine learning, they will be able to develop
                                                                 customized solutions which will target a specific
             “When we import technology we have no ability to    dysfunction with less or no side effects.
             change it and to innovate,” says Dr. Valiante. “At
             CRANIA, we will have this unique multi-disci-       „  READ MORE



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